In the United States, the incidence of very premature delivery before 32 weeks gestation is 1.6% for singleton gestations. This increases to 36% for triplet pregnancies [2]. Spontaneous triplets in a uterine didelphys are an extreme rarity. Factors that separate our case from those previously published include use of cerclage, and all three babies surviving and doing well today. Our case shows that expectant management is an alternative to selective reduction for desiring patients with triplets in a uterus didelphys. “
“Thrombocytopenia is a common finding during pregnancy. Isolated

thrombocytopenia has a vast aetiology, but in most cases it is mild and pregnancy induced. Sometimes Selleck Bafilomycin A1 thrombocytopenia is accompanied by schistocytes in

the blood smear. This is of clinical importance because their presence indicates an endothelial dysfunction, which is referred to as thrombotic microangiopathy (TMA) [1]. The differential diagnosis of isolated thrombocytopenia is quite different from the differential diagnosis of TMA’s: 1) severe pre-eclampsia; 2) HELLP syndrome (Coombs-negative haemolysis, elevated liver enzymes and low platelet count) [1]; 3) thrombotic thrombocytopenic purpura (TTP); 4) haemolytic–uremic syndrome (HUS) [1], [2] and [3] and 5) systemic lupus erythematosus (SLE) [4]. To the concerned physicians selleck these five entities together are a inhibitors diagnostic challenge in pregnancy because of their overlapping features and the requirement of different Rolziracetam treatment regimens. Here we describe a case of postpartum thrombocytopenia

caused by TMA in pregnancy, in which the difficulties in establishing the cause of the TMA are highlighted. A 27 year old Caucasian woman, gravida 1, was admitted to the hospital for induction of labour because she was nearly post-term (40 + 5 weeks). Cardiotocography (CTG) on admission was non-reassuring with a saltatory pattern. Her blood pressure was 110/70 mm Hg on the day of admission and her medical history comprised erysipelas with lymphangitis, and recurrent sinusitis due to a septum deviation. Her membranes were ruptured artificially and the amniotic fluid was meconium-stained. CTG was optimal during labour, showing no signs of foetal distress. She received 150 mg of pethidine (meperidine) s.c. for pain. The second stage took 45 min and a healthy son was born. He had a birth weight of 3760 g and the Apgar-scores were 7 immediately after birth, and 10 after five insufflations with oxygen. After delivery 10 U of oxytocin s.c. was administered and the placenta was delivered 30 min later. A total blood loss of 300 mL was documented. Twenty-three minutes later her blood pressure declined to 58/32 mm Hg, the heart rate was 115 bpm and O2-saturation was 98%. She also felt drowsy and at physical examination the uterus was well contracted. She received oxygen, 20 U of oxytocin s.c., 0.