From the entire study population, 4.1% had preeclampsia or eclampsia (n=44,004), 1.8% had chronic hypertension (n=19,647), 1.1% of patients were classified as obese (n=11,936), 0.7% had pregestational diabetes (n=7,474), 0.4% had HIV (n=4,665), and 0.01% had pulmonary hypertension (n=166). Preeclampsia or eclampsia (adjusted odds ratio [OR], 8.1; 95% confidence interval [CI], 5.5-12.1), chronic hypertension (adjusted OR, 7.7; 95% CI 4.7-12.5), underlying maternal obesity (adjusted OR, 2.9; 95% CI 1.1-8.1), pregestational diabetes (adjusted OR, 3.3; 95% CI 1.3-8.1), HIV (adjusted OR, 7.7; 95% CI 3.4-17.8), and pulmonary hypertension

(adjusted OR, 65.1; 95% CI 15.8-269.3) were Poziotinib order associated with an increased risk of death during the delivery hospitalization.

CONCLUSION: The presence of maternal disease significantly increases the odds of maternal mortality at the time of delivery hospitalization.”
“Until recently there was little to offer young women with cancer facing chemotherapy, radiotherapy or surgery and the probability

of premature menopause and sterility. The selleckchem first ‘frozen egg’ baby was born in 1986, but success rates were so low that egg freezing was neglected. Three technological developments in assisted reproduction treatment (intracytoplasmic sperm injection, dehydro-cryoprotectants and vitrification) have transformed this picture and now young women with frozen eggs have the same probability of a live birth per embryo transfer as women undergoing conventional IVF. For many women it is not cancer but the passage of

time that denies them a chance of motherhood. Social, educational and financial pressures often lead them to delay starting a family until their late thirties, by which time the chance of success is compromised by low fecundity rates and an increased risk of miscarriage if they become pregnant. Donor eggs are not an option for many because of supply constraints and ethical concerns. Freezing a woman’s eggs at age 30 literally ‘freezes in EX 527 mw time’ her fertility potential and gives her the chance of a healthy pregnancy at a time of her choosing. The role of oocyte cryopreservation in the context of social egg freezing is discussed. (C) 2011, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.”
“A hospital registry is a collection of prospectively recorded information about patients who have a specific condition or who received a specific type of treatment. Hospital registries are beneficial for the patient, physicians, and administrators and serve several purposes, with the primary purpose being quality control. This article focuses on the role of registries at the hospital level and their advantages compared with other data sets. We also discuss how to implement a hospital registry and how to ascertain registry quality.