“
“Owing to the enhanced sensitivity of nonlinear acoustic methods to material damage, the nonlinear Lamb wave propagation is pertinent to the nondestructive evaluation of platelike structures, and it is typically manifested as generation of higher harmonics. For dispersive waves such as Lamb waves, however, the cumulative growth of harmonics requires that the primary mode and the generated higher Selleck Proteasome inhibitor harmonic modes possess

identical phase and group velocities. In this paper, this issue of the phase and group velocity matching in Lamb waves is explored based on a systematic analysis of the Rayleigh-Lamb frequency equations. The analysis shows that for certain values of the phase velocity, the Rayleigh-Lamb frequency equations are satisfied at equi-spaced frequencies which are multiples of the smallest. Such frequencies, together with the corresponding phase velocities and the Lamb modes, are determined analytically. Four such types of Lamb modes are identified: (i) Lame modes, (ii) symmetric modes with dominant longitudinal displacements, (iii) intersections of symmetric and antisymmetric modes and (iv) extra Rayleigh modes. For the first three types, it is also established that the primary and the harmonic modes have the same group velocity, and that the surface motion of the plate is featured with

vanishing vertical or horizontal Sotrastaurin clinical trial displacements. In contrast to these three types, the fourth type only exists for a special range of the transverse to longitudinal wave speeds of the solid. This type is not featured with a common group velocity, and neither of the vertical

or horizontal displacement vanishes on the plate surfaces. The obtained results are summarized as tables, and demonstrated graphically on the dispersion curves for aluminum as well as iron plates. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3569864]“
“Curcumin, a natural polyphenolic flavonoid extracted from the rhizome of Curcuma longa L., has many beneficial biological activities. However, there are relatively few reports of the effects of curcumin on pathogen infections. This study examined the effect of curcumin on a Vibrio vulnificus infection. The cytotoxicity Ion Channel Ligand Library clinical trial of V. vulnificus to HeLa cells was significantly inhibited by curcumin (at 10 or 30 similar to mu M). To further examine the inhibitory mechanism of curcumin against V. vulnificus-mediated cytotoxicity, the level of bacterial growth, bacterial motility, cell adhesion, RTX toxin expression and host cell reactions were evaluated. Curcumin inhibited V. vulnificus growth in HI broth. Curcumin inhibited both bacterial adhesion and RTX toxin binding to the host cells, which can be considered the major protective mechanisms for the decrease in V. vulnificus cytotoxicity.